DRAXIN anticorps (C-Term)

N° du produit ABIN1887201

Détail du produit anti-DRAXIN anticorps

Antigène: DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DRAXIN est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): At least three isoforms of Neucrin are known to exist, this antibody will detect the two shorter isoforms. Neucrin antibody is predicted to not cross-react with RILP.

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the carboxy terminus of human Neucrin.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur DRAXIN

Antigène: DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))

Autre désignation: NEUCRIN (DRAXIN Produits)

Synonymes: anticorps C1orf187, anticorps draxin, anticorps AGPA3119, anticorps UNQ3119, anticorps neucrin, anticorps 2610109H07Rik, anticorps MGC113312, anticorps dorsal inhibitory axon guidance protein, anticorps DRAXIN, anticorps Draxin, anticorps draxin

Sujet: Neucrin, also known as Draxin, is a repulsive guidance protein for the spinal cord and forebrain commissures.It is thought to act as an antagonist of canonical Wnt signaling by inhibiting the stabilization of cytosolic beta-catenin.Ectopically expressed neucrin inhibited growth or caused misrouting of chick spinal cord commissural axons in vivo while Neucrin-null mice showed defasciculation of spinal cord commissural axons and an absence of all forebrain commisures.Other experiments in mice have shown that olfactory bulb axonal outgrowth is inhibited by Neucrin, suggesting that Neucrin functions as an inhibitory guidance cue for olfactory bulb axons.
Synonyms: Draxin, dorsal repulsive axon guidance protein