SEC62 anticorps (C-Term)

N° du produit ABIN1887427

Détail du produit anti-SEC62 anticorps

Antigène: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SEC62 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): SEC62 antibody is predicted to not cross-react with other SEC proteins. Multiple isoforms of SEC62 are known to exist.

Purification: Affinity chromatography purified via peptide column

Immunogène: SEC62 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human SEC62.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur SEC62

Antigène: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Autre désignation: SEC62 (TLOC1 Produits)

Synonymes: anticorps tloc1, anticorps TLOC1, anticorps wu:fb57b06, anticorps zgc:114073, anticorps Dtrp1, anticorps HTP1, anticorps TP-1, anticorps 3100002M17Rik, anticorps AI844545, anticorps AW545092, anticorps Tloc1, anticorps Ab2-292, anticorps SEC62 homolog, preprotein translocation factor S homeolog, anticorps SEC62 homolog, preprotein translocation factor, anticorps membrane unit of ER protein translocation apparatus, anticorps SEC62 homolog (S. cerevisiae), anticorps sec62.S, anticorps SEC62, anticorps sec62, anticorps Sec62

Sujet: SEC62 is an integral membrane protein located in the rough endoplasmic reticulum (ER) and is part of the SEC61-SEC62-SEC63 complex that is the central component of the protein translocation apparatus of the ER membrane.It is speculated that SEC61-SEC62-SEC63 may perform post-translational protein translocation into the ER and might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway.Silencing of this gene with RNAi dramatically reduced the migration and invasive potential of numerous tumor cell lines, suggesting that it may be an attractive target for therapy of various tumors.
Synonyms: Translocation protein 62, HTP1, TP-1, DTRP1, TLOC1

NCBI Accession: NP_003253