PAK7 anticorps (Center)

N° du produit ABIN1887485

Détail du produit anti-PAK7 anticorps

Antigène: PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 13 amino acid peptide from near the center of human PAK5.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur PAK7

Antigène: PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

Autre désignation: PAK5 (PAK7 Produits)

Synonymes: anticorps PAK5, anticorps pak5, anticorps 2900083L08Rik, anticorps 6430627N20, anticorps Pak5, anticorps PAK-5, anticorps PAK-7, anticorps p21 (RAC1) activated kinase 5, anticorps p21 (RAC1) activated kinase 5 L homeolog, anticorps p21 protein (Cdc42/Rac)-activated kinase 7, anticorps p21 (RAC1) activated kinase 7, anticorps PAK5, anticorps pak5.L, anticorps Pak7

Sujet: The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac.They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding.Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding.The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility.Much less is known about the second group, which includes PAK4, 5 and 6.These proteins are not activated by Cdc42/Rac binding.PAK5 was initially identified as a kinase expressed primarily in brain that while possessing a kinase domain and GTPase binding domain similar to PAK4 and PAK6, is completely different from both.Expression of PAK5 in neural based cell lines resulted in neurite outgrowth suggesting that PAK5 may be involved in regulating the cytoskeletal changes necessary for promoting neurite outgrowth.Other experiments suggest that unlike the other PAKs, PAK5 may inhibit apoptosis by phosphorylating the Bcl-2 family member Bad.
Synonyms: p21-activated kinase 5

UniProt: Q9P286