UNG anticorps (Center)

N° du produit ABIN1887491

Détail du produit anti-UNG anticorps

Antigène: UNG (Uracil-DNA Glycosylase (UNG))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNG est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: 13 amino acid peptide from near the center of human UNG2.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur UNG

Antigène: UNG (Uracil-DNA Glycosylase (UNG))

Autre désignation: UNG2 (UNG Produits)

Synonymes: anticorps DGU, anticorps HIGM4, anticorps HIGM5, anticorps UDG, anticorps UNG1, anticorps UNG15, anticorps UNG2, anticorps ung, anticorps zgc:56102, anticorps PSPTO4236, anticorps BA5648, anticorps ECK2578, anticorps JW2564, anticorps An02g14790, anticorps AO090001000732, anticorps DDBDRAFT_0204444, anticorps DDBDRAFT_0214910, anticorps DDB_0204444, anticorps DDB_0214910, anticorps uracil-DNA glycosylase, anticorps uracil DNA glycosylase, anticorps uracil DNA glycosylase a, anticorps uracil-DNA glycosylase Ung, anticorps uracil-DNA-glycosylase, anticorps uracil DNA glycosylase L homeolog, anticorps uracil glycosylase, anticorps temporal expression: early, anticorps ung, anticorps ung2, anticorps Ung, anticorps UNG, anticorps unga, anticorps STY2840, anticorps ung.L, anticorps ANI_1_3358024, anticorps AOR_1_1318164, anticorps uglA, anticorps Arnit_2731, anticorps D4R

Classe de substances: Viral Protein

Sujet: The human uracil-DNA glycosylase (UNG) gene encodes both mitochondrial (UNG1) and nuclear (UNG2) forms through differentially regulated promotes and alternative splicing.UNG2 is the major enzyme in the base excision repair pathway that removes uracil residues from DNA that arise through either misincorporation during replication or cytosine deamination.UNG2 can also be bound by the HIV-1 integrase and incorporated into the virion particle, suggesting that it is required to remove uracils from the viral genome.As the intrinsic antiviral protein APOBEC3G generates numerous uracils in the HIV genome during its replication, it may be that the UNG2 contributes to the APOBEC3G-mediated loss of infectivity by generating abasic sites in the viral genome.This UNG2 antibody will not cross-react with UNG1.
Synonyms: Uracil-DNA glycosylase 2, UDG2

NCBI Accession: NP_066970

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response