EFCAB4A anticorps (Center)

N° du produit ABIN1887557

Détail du produit anti-EFCAB4A anticorps

Antigène: EFCAB4A (EF-Hand Calcium Binding Domain 4A (EFCAB4A))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EFCAB4A est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide near the center of human EFCAB4A.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur EFCAB4A

Antigène: EFCAB4A (EF-Hand Calcium Binding Domain 4A (EFCAB4A))

Autre désignation: EFCAB4A (EFCAB4A Produits)

Synonymes: anticorps CRACR2B, anticorps 6330520A15Rik, anticorps BC026645, anticorps Cracr2a, anticorps Efcab4, anticorps RGD1560911, anticorps zgc:158448, anticorps calcium release activated channel regulator 2B, anticorps cracr2b, anticorps CRACR2B, anticorps Cracr2b

Sujet: EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation.It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.
Synonyms: EF-hand calcium binding domain 4A, Calcium release-activated calcium channel regulator 2, CRACR2B

NCBI Accession: NP_775855