WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Conseil sur la manipulation
Avoid freezing and thawing repeatly.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Antigène
SCARB2
(Scavenger Receptor Class B, Member 2 (SCARB2))
anticorps cd36l2, anticorps fi13c07, anticorps chunp6914, anticorps wu:fi13c07, anticorps SCARB2, anticorps scarb2, anticorps AMRF, anticorps CD36L2, anticorps EPM4, anticorps HLGP85, anticorps LGP85, anticorps LIMP-2, anticorps LIMPII, anticorps SR-BII, anticorps 9330185J12Rik, anticorps Cd36l2, anticorps MLGP85, anticorps LimpII, anticorps scavenger receptor class B, member 2a, anticorps scavenger receptor class B member 2, anticorps scavenger receptor class B, member 2, anticorps scarb2a, anticorps SCARB2, anticorps scarb2, anticorps Scarb2
Sujet
The lysosomal integral membrane protein 2 (LIMP2) is a heavily glycosylated type III transmembrane protein, the majority of which exists in the lumen of the lysosome and a cytoplasmic domain of approximately 20 amino acids.A deficiency of LIMP2 in mice causes uretic pelvic junction obstruction, deafness, and peripheral neuropathy associated with impaired vesicular trafficking and distribution of apically expressed proteins.More recently, LIMP2 was shown to act as a receptor to bind beta-glucocerebrosidase, the enzyme defective in Gaucher disease, a lysosomal storage disorder.LIMP2-deficient mice showed missorted as well as secreted beta-glucocerebrosidase, suggesting that LIMP2 also functions as the mannose-6-phosphate-independent trafficking receptor. Synonyms: Lysosomal integral membrane protein 2, CD36L2, Scavenger receptor class B member 2, SR-B2, SCARB2