TIMD4
Reactivité: Humain
ELISA
Hôte: Lapin
Polyclonal
Biotin
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Conseil sur la manipulation
Avoid freezing and thawing repeatly.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Antigène
TIMD4
(T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))
anticorps RGD1564516, anticorps MGC99322, anticorps TIMD4, anticorps B430010N18Rik, anticorps TIM-4, anticorps Tim4, anticorps SMUCKLER, anticorps TIM4, anticorps T-cell immunoglobulin and mucin domain containing 4, anticorps T-cell immunoglobulin and mucin domain containing 4 L homeolog, anticorps T cell immunoglobulin and mucin domain containing 4, anticorps Timd4, anticorps TIMD4, anticorps timd4.L
Sujet
The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity.TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production.Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain.The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma. Synonyms: T cell immunoglobulin and mucin domain containing protein 4, T cell membrane protein 4, SMUCKLER