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LIF anticorps (Center)

LIF Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1887617
  • Antigène Voir toutes LIF Anticorps
    LIF (Leukemia Inhibitory Factor (LIF))
    Épitope
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivité
    • 47
    • 17
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 43
    • 8
    • 2
    • 2
    • 2
    • 2
    Lapin
    Clonalité
    • 52
    • 7
    Polyclonal
    Conjugué
    • 41
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LIF est non-conjugé
    Application
    • 47
    • 26
    • 24
    • 15
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    16 amino acid peptide near the center of human LIF.
    Top Product
    Discover our top product LIF Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Conseil sur la manipulation
    Avoid freezing and thawing repeatly.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • Antigène
    LIF (Leukemia Inhibitory Factor (LIF))
    Autre désignation
    LIF (LIF Produits)
    Synonymes
    anticorps CDF, anticorps DIA, anticorps HILDA, anticorps MLPLI, anticorps LIF, interleukin 6 family cytokine, anticorps leukemia inhibitory factor, anticorps LIF, anticorps Lif
    Sujet
    LIF is a pleiotropic cytokine with roles in several different systems.It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface.LIF was initially recognized by its ability to induce terminal differentiation of myeloid leukemic cells.It is a member of the IL-6 cytokine superfamily and can be highly glycosylated.LIF signaling is transduced through the LIF-R/gp130 receptor complex, leading to the phosphorylation and activation of the JAK/STAT pathway.Recent evidence shows that LIF inhibits cardiomyogenesis in embryonic stem cells via STAT3 activation.
    Synonyms: Leukemia inhibitory factor, CDF, DIA, HILDA, MLPLI
    NCBI Accession
    NP_002300
    Pathways
    Signalistation JAK/STAT, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding
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