GOPC anticorps (Center)

N° du produit ABIN1887642

Détail du produit anti-GOPC anticorps

Antigène: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Épitope: Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GOPC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide from near the center of human PIST.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur GOPC

Antigène: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Autre désignation: PIST (GOPC Produits)

Synonymes: anticorps DKFZp459H2130, anticorps 2210402P09Rik, anticorps AI844555, anticorps CAL, anticorps FIG, anticorps GOPC1, anticorps PIST, anticorps fe38f01, anticorps wu:fe38f01, anticorps zgc:56254, anticorps zgc:65853, anticorps dJ94G16.2, anticorps cal, anticorps gopc1, anticorps pist, anticorps golgi associated PDZ and coiled-coil motif containing, anticorps golgi-associated PDZ and coiled-coil motif containing, anticorps golgi-associated PDZ and coiled-coil motif containing S homeolog, anticorps GOPC, anticorps Gopc, anticorps gopc, anticorps gopc.S

Sujet: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells.It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components and is negatively regulated by TOR (Target of rapamycin).PIST, a PDZ-containing protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6.Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.
Synonyms: Golgi associated PDZ and coiled-coil motif containing, GOPC

Pathways: Maintenance of Protein Location, Asymmetric Protein Localization