KCNK18 anticorps (Center)

N° du produit ABIN1887646

Détail du produit anti-KCNK18 anticorps

Antigène: KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNK18 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide from near the center of human TRESK.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur KCNK18

Antigène: KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))

Autre désignation: TRESK (KCNK18 Produits)

Synonymes: anticorps K2p18.1, anticorps MGR13, anticorps TRESK, anticorps TRESK-2, anticorps TRESK2, anticorps TRIK, anticorps Gm781, anticorps Tresk, anticorps Tresk-2, anticorps Trik, anticorps potassium two pore domain channel subfamily K member 18, anticorps potassium channel, subfamily K, member 18, anticorps KCNK18, anticorps Kcnk18

Sujet: TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes.TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine.It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin.Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.
Synonyms: KCNK18, Potassium channel subfamily K member 18, TRIK, TRESK2

NCBI Accession: NP_862823