NLRC3 anticorps (Center)

N° du produit ABIN1887754

Détail du produit anti-NLRC3 anticorps

Antigène: NLRC3 (NLR Family, CARD Domain Containing 3 (NLRC3))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRC3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: NOD3 antibody was raised against an 18 amino acid peptide near the center of human NOD3.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur NLRC3

Antigène: NLRC3 (NLR Family, CARD Domain Containing 3 (NLRC3))

Autre désignation: NOD3 (NLRC3 Produits)

Synonymes: anticorps NLRC3, anticorps nod3, anticorps NLR-A3, anticorps NOD3, anticorps CLR16.2, anticorps D230007K08Rik, anticorps mFLJ00348, anticorps Nlrc3-ps1, anticorps RGD1304902, anticorps NLR family CARD domain containing 3, anticorps NLR family, CARD domain containing 3, anticorps NLRC3, anticorps nlrc3, anticorps Nlrc3

Sujet: NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense.NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells.NOD3 inhibits NF-kappaB, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells.
Synonyms: Nucleotide-binding oligomerization domain containing 3, NLRC3, CLR16.2