TLR5 anticorps (Center)

N° du produit ABIN1887763

Détail du produit anti-TLR5 anticorps

Antigène: TLR5 (Toll-Like Receptor 5 (TLR5))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: Peptide corresponding to 16 amino acids near the center of human TLR5.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur TLR5

Antigène: TLR5 (Toll-Like Receptor 5 (TLR5))

Autre désignation: TLR5 (TLR5 Produits)

Synonymes: anticorps SLEB1, anticorps TIL3, anticorps TLR-5, anticorps sleb1, anticorps til3, anticorps tlr-5, anticorps tlr5, anticorps toll like receptor 5, anticorps toll-like receptor 5, anticorps toll like receptor 5 L homeolog, anticorps toll-like receptor 5b, anticorps TLR5, anticorps Tlr5, anticorps tlr5.L, anticorps tlr-5, anticorps tlr5b

Sujet: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila.These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection.TLR5 recognizes flagellin from both Gram-positive and Gram-negative bacteria and will cause the activation of NF-kappaB, leading to the activation of TNF-alpha and other cytokines.A common TLR5 stop codon polymorphism that disrupts TLR5 signaling is associated with susceptibility to Legionnaires' disease and demonstrates the importance of TLR5 in the innate immune response.
Synonyms: Toll-like receptor 5

NCBI Accession: NP_003259

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades