BIM anticorps (Center)

N° du produit ABIN1887766

Détail du produit anti-BIM anticorps

Antigène: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: Peptide corresponding to amino acids near the center of human Bim the sequence is identical to that of mouse and differs from that of rat by one amino acid.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur BIM

Antigène: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Autre désignation: Bim (BCL2L11 Produits)

Synonymes: anticorps bim, anticorps BAM, anticorps BIM, anticorps BOD, anticorps 1500006F24Rik, anticorps Bim, anticorps Bod, anticorps BimL, anticorps BIMEL, anticorps BCL2-like 11, anticorps BCL2 like 11, anticorps BCL2-like 11 (apoptosis facilitator), anticorps bcl2l11, anticorps BCL2L11, anticorps Bcl2l11

Sujet: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death.Bcl-2 homology 3 (BH3) domain is a potent death domain.BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family.A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat.Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w.Bim/BOD induces apoptosis.The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
Synonyms: BOD

Poids moléculaire: 23 kDa

UniProt: O43521

Pathways: Signalisation PI3K-Akt, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity