CCR8 anticorps (Extracellular Loop)

N° du produit ABIN1887798

Détail du produit anti-CCR8 anticorps

Antigène: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Épitope: Extracellular Loop

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR8 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: Peptide corresponding to amino acids 183 to 201 of human CCR8, which locate in the second extracellular loop.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur CCR8

Antigène: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Autre désignation: CCR8 (CCR8 Produits)

Synonymes: anticorps CC-CKR-8, anticorps CCR-8, anticorps CDw198, anticorps CKRL1, anticorps CMKBR8, anticorps CMKBRL2, anticorps CY6, anticorps GPRCY6, anticorps TER1, anticorps C-C, anticorps C-C CKR-8, anticorps CKR-8, anticorps Cmkbr8, anticorps mCCR8, anticorps C-C motif chemokine receptor 8, anticorps chemokine (C-C motif) receptor 8, anticorps CCR8, anticorps Ccr8

Sujet: CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection.The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR1.The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8.Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains.CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309.CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.

Poids moléculaire: 50 kDa