ZNF536 anticorps (N-Term)

N° du produit ABIN1887978

Détail du produit anti-ZNF536 anticorps

Antigène: ZNF536 (Zinc Finger Protein 536 (ZNF536))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF536 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid peptide from near the amino terminus of human ZNF536.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur ZNF536

Antigène: ZNF536 (Zinc Finger Protein 536 (ZNF536))

Autre désignation: ZNF536 (ZNF536 Produits)

Synonymes: anticorps 9630010P11Rik, anticorps Znf536, anticorps mKIAA0390, anticorps RGD1563363, anticorps zinc finger protein 536, anticorps ZNF536, anticorps Zfp536

Sujet: ZNF536 is a recently identified zinc-finger protein that is expressed primarily in the developing nervous system and the cerebral cortex, hippocampus, and hypothalamus.ZNF536 possess ten zinc fingers and interacts with CtBP1, a corepressor for gene transcription.It is most closely related to transcriptional repressor ZNF219.Overexpression of ZNF536 in embryonic stem cells dramatically reduced the mRNA levels of neuronal marker genes such as Pax6, MAP2, and beta-tubulin III following retinoic acid (RA)-induced differentiation, while depletion of ZNF536 via RNAi resulted in elevated mRNA levels of these genes, indicating its role in inhibiting neuronal cell differentiation.Overexpression of RA receptor a rescues the inhibitory role of ZNF536, suggesting that ZNF536 might inhibit RA response element-mediated transcriptional activity.
Synonyms: Zinc finger protein 536

NCBI Accession: NP_055532

Pathways: Retinoic Acid Receptor Signaling Pathway