INSM1 anticorps (N-Term)

N° du produit ABIN1888097

Détail du produit anti-INSM1 anticorps

Antigène: INSM1 (Insulinoma-Associated 1 (INSM1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INSM1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid peptide from near the amino terminus of human IA-1.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur INSM1

Antigène: INSM1 (Insulinoma-Associated 1 (INSM1))

Autre désignation: IA-1 (INSM1 Produits)

Synonymes: anticorps IA-1, anticorps IA1, anticorps INSM-1, anticorps Insm1, anticorps fc13a09, anticorps wu:fc13a09, anticorps zINSM-1, anticorps zgc:63866, anticorps INSM1, anticorps ia-1, anticorps zgc:77257, anticorps INSM transcriptional repressor 1, anticorps insulinoma-associated 1, anticorps insulinoma-associated 1b, anticorps insulinoma associated 1, anticorps insulinoma associated 1 L homeolog, anticorps insulinoma-associated 1a, anticorps INSM1, anticorps Insm1, anticorps insm1b, anticorps insm1, anticorps insm1.L, anticorps insm1a

Sujet: IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system.Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid- and hindbrain, spinal cord, retina, and olfactory bulb.It is thought that IA-1 functions as a transcriptional repressor, and is a part of several signaling pathways including those of Notch and sonic hedgehog in addition to that of Ngn3 during pancreatic endocrine cell differentiation.IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100% of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.
Synonyms: Insulinoma-associated 1, INSM1, IA1

NCBI Accession: NP_002187