LZTS2 anticorps (N-Term)

N° du produit ABIN1888112

Détail du produit anti-LZTS2 anticorps

Antigène: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LZTS2 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): LZTS2 antibody is predicted to not cross-react with other LZTS family members

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid peptide near the amino terminus of human LZTS2.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur LZTS2

Antigène: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Autre désignation: LZTS2 (LZTS2 Produits)

Synonymes: anticorps lapser1, anticorps MGC89253, anticorps si:dkey-250a11.1, anticorps LAPSER1, anticorps BC014695, anticorps mKIAA1813, anticorps Lapser1, anticorps leucine zipper, putative tumor suppressor 2, anticorps leucine zipper tumor suppressor 2, anticorps leucine zipper, putative tumor suppressor 2a, anticorps leucine zipper, putative tumor suppressor 2 S homeolog, anticorps lzts2, anticorps LZTS2, anticorps lzts2a, anticorps Lzts2, anticorps lzts2.S

Sujet: The leucine zipper putative tumor suppressor 2 (LZTS2, also known as LAPSER1), a member of the LZTS family, is a negative regulator of the Wnt signaling pathway.It represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.LZTS2 is involved in cytokinesis and regulates katanin-mediated microtubule severing and release from the centrosome.LZTS2 may negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon.LZTS2 is highly expressed in testis and prostate, but it is deleted in multiple cancers, including prostate tumors, suggesting that LZTS2 acts as a potential tumor suppressor.
Synonyms: Leucine zipper putative tumor suppressor 2, LAPSER1

NCBI Accession: NP_115805