TLR6 anticorps (N-Term)
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- Antigène Voir toutes TLR6 Anticorps
- TLR6 (Toll-Like Receptor 6 (TLR6))
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Épitope
- N-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TLR6 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Peptide corresponding to 15 amino acids near the amino terminus of human TLR6.
- Top Product
- Discover our top product TLR6 Anticorps primaire
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Conseil sur la manipulation
- Avoid freezing and thawing repeatly.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- Antigène
- TLR6 (Toll-Like Receptor 6 (TLR6))
- Autre désignation
- TLR6 (TLR6 Produits)
- Synonymes
- anticorps TLR1, anticorps TLR16, anticorps CD286, anticorps TLR-6, anticorps toll-like receptor 1 family member A, anticorps toll like receptor 6, anticorps toll-like receptor 6, anticorps TLR1A, anticorps TLR6, anticorps Tlr6
- Sujet
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Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila.These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection.TLR6 was first identified as a close homolog of TLR1, sharing 69% sequence identify.Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 dimers coordinate macrophage activation by Gram-positive bacteria and the yeast cell wall particle zymosan.Activation of these complexes not only initiates pro-inflammatory cascades, but also can lead to apoptotic responses.
Synonyms: Toll-like receptor 6 - NCBI Accession
- NP_006059
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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