CAMK2A anticorps (AA 7-20)

N° du produit ABIN190687

Détail du produit anti-CAMK2A anticorps

Antigène: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Épitope: AA 7-20

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAMK2A est non-conjugé

Application: Western Blotting (WB)

Fonction: Anti-CaMKII Rabbit Polyclonal Antibody

Réactivité croisée: Poulet, Boeuf (Vache), Cobaye, Hamster, Humain, Souris, Lapin, Rat

Purification: Affinity - Purified

Immunogène: Synthetic peptide corresponding to aa 7-20 (N-terminus) of rat CaMKII delta isoform conjugated to KLH.

Information d'application

Indications d'application: Immunoblotting: Use at 1-5 μg/mL. A band of ~50-60 kDa is detected.
Immunohistochemistry: use at 1-10 μg/mL.
These are recommended concentrations.
Endusers should determine optimal concentrations for their applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Concentration: Lot specific

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: This antibody is stable for at least one (1) year at -20°C.

Détails sur CAMK2A

Antigène: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Autre désignation: CAMK2A (CAMK2A Produits)

Synonymes: anticorps camk2, anticorps camk2b, anticorps zgc:112538, anticorps zgc:123320, anticorps CAMKA, anticorps CaMKII, anticorps R74975, anticorps mKIAA0968, anticorps PK2CDD, anticorps PKCCD, anticorps calcium/calmodulin dependent protein kinase II alpha, anticorps calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog, anticorps calcium/calmodulin-dependent protein kinase II alpha, anticorps CAMK2A, anticorps camk2a.S, anticorps camk2a, anticorps Camk2a

Sujet: Calcium/calmodulin-dependent protein kinase type II subunit α,Calmodulin-dependent protein kinase II (CaMKII) is a serine/threonine-specific protein kinase that is regulated by the Ca2+/calmodulin complex. CaMKII is involved in many signaling cascades and is thought to be an important mediator of learning and memory. CaMKII is also necessary for Ca2+ homeostasis and reuptake in cardiomyocytes, chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation. CaMKII has 28 different isoforms that derive from the alpha, beta, gamma, and delta genes. Misregulation of CaMKII is linked to Alzheimer's disease, Angelman syndrome, and heart arrhythmia.,CaM kinase II subunit α, CaMK-II subunit α, EC 2.7.11.17

ID gène: 815

NCBI Accession: NP_741960

Pathways: Signalisation WNT, Interferon-gamma Pathway, Myometrial Relaxation and Contraction