MUC1 anticorps (AA 24-273) (HRP)

N° du produit ABIN1993187

Détail du produit anti-MUC1 anticorps (HRP)

Antigène: MUC1 (Mucin 1 (MUC1))

Épitope: AA 24-273

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUC1 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Mucin-1 protein (24-273AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MUC1

Antigène: MUC1 (Mucin 1 (MUC1))

Autre désignation: MUC1 (MUC1 Produits)

Synonymes: anticorps CA 15-3, anticorps CD227, anticorps EMA, anticorps H23AG, anticorps KL-6, anticorps MAM6, anticorps MCKD1, anticorps MUC-1, anticorps MUC-1/SEC, anticorps MUC-1/X, anticorps MUC1/ZD, anticorps PEM, anticorps PEMT, anticorps PUM, anticorps Muc-1, anticorps mucin 1, cell surface associated, anticorps mucin 1, transmembrane, anticorps MUC1, anticorps Muc1

Sujet:

Background: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. Ref.26 Ref.37 Ref.40 Ref.45 Ref.46 Ref.49 Ref.52 Ref.53 Ref.56.The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.

Aliases: ADMCKD antibody, ADMCKD1 antibody, Breast carcinoma associated antigen DF3 antibody, Breast carcinoma-associated antigen DF3 antibody, CA 15-3 antibody, CA15 3 antibody, CA15 3 antigen antibody, CA15-3 antibody, CA15.3 antibody, Cancer antigen 15-3 antibody, Carcinoma associated mucin antibody, Carcinoma-associated mucin antibody, CD 227 antibody, CD227 antibody, DF3 antigen antibody, EMA antibody, Episialin antibody, Epithelial Membrane Antigen antibody, H23 antigen antibody, H23AG antibody, KL 6 antibody, KL-6 antibody, KL6 antibody, Krebs von den Lungen-6 antibody, MAM 6 antibody, MAM6 antibody, MCD antibody, MCKD antibody, MCKD1 antibody, Medullary cystic kidney disease 1 (autosomal dominant) antibody, Medullary cystic kidney disease, autosomal dominant antibody, MUC 1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1 antibody, MUC1-alpha antibody, MUC1-beta antibody, MUC1-CT antibody, MUC1-NT antibody, MUC1/ZD antibody, MUC1_HUMAN antibody, Mucin 1 antibody, Mucin 1 cell surface associated antibody, Mucin 1 transmembrane antibody, Mucin 1, cell surface associated antibody, Mucin-1 subunit beta antibody, Peanut reactive urinary mucin antibody, Peanut-reactive urinary mucin antibody, PEM antibody, PEMT antibody, Polymorphic epithelial mucin antibody, PUM antibody, Tumor associated epithelial membrane antigen antibody, Tumor associated epithelial mucin antibody, Tumor associated mucin antibody, Tumor-associated epithelial membrane antigen antibody, Tumor-associated mucin antibody

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling