Perforin 1 anticorps (AA 22-554)
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- Antigène Voir toutes Perforin 1 (PRF1) Anticorps
- Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
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Épitope
- AA 22-554
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Perforin 1 est non-conjugé
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Application
- ELISA
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Perforin-1 protein (22-554AA)
- Isotype
- IgG
- Top Product
- Discover our top product PRF1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
- Autre désignation
- PRF1 (PRF1 Produits)
- Synonymes
- anticorps FLH2, anticorps HPLH2, anticorps P1, anticorps PFN1, anticorps PFP, anticorps PRF1, anticorps Pfn, anticorps Pfp, anticorps Prf-1, anticorps Cyta, anticorps RATCYTA, anticorps LOC443187, anticorps perforin, anticorps prf1, anticorps cytolysin, anticorps perforin-1, anticorps perforin-1-like, anticorps perforin 1, anticorps perforin 1 (pore forming protein), anticorps perforin, anticorps perforin 1 L homeolog, anticorps PRF1, anticorps Prf1, anticorps LOC443187, anticorps prf1, anticorps prf1.L
- Sujet
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Background: Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
Aliases: Cytolysin antibody, FLH2 antibody, HPLH2 antibody, Lymphocyte pore-forming protein antibody, P1 antibody, PERF_HUMAN antibody, perforin 1 (pore forming protein) antibody, Perforin 1 antibody, Perforin-1 antibody, PFP antibody, PGFL antibody, PIGF antibody, PIGF-2 antibody, PLGF antibody, Pore forming protein antibody, prf1 antibody, SHGC-10760 antibody
- UniProt
- P14222
- Pathways
- Apoptose, Caspase Cascade in Apoptosis
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