HPV16 E7 anticorps (Middle Region) (AbBy Fluor® 555)
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- Antigène Voir toutes HPV16 E7 (HPV-16 E7) Anticorps
- HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))
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Épitope
- Middle Region
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Reactivité
- Human Papillomavirus 16 (HPV-16)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HPV16 E7 est conjugé à/à la AbBy Fluor® 555
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
- Specificité
- This antibody may also detect HPV35-E7
- Réactivité croisée
- Humain, Virus
- Réactivité croisée (Details)
- HPV16
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from middle of HPV16-E7
- Isotype
- IgG
- Top Product
- Discover our top product HPV-16 E7 Anticorps primaire
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- Indications d'application
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))
- Abstract
- HPV-16 E7 Produits
- Synonymes
- anticorps transforming protein E7, anticorps E7
- Classe de substances
- Viral Protein
- Sujet
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Synonyms: Protein E7, E7
Background: Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host inteferon alpha.
- ID gène
- 1489079
- UniProt
- P03129
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