ERCC6 anticorps (AA 201-300) (Biotin)

N° du produit ABIN2173880

Détail du produit anti-ERCC6 anticorps (Biotin)

Antigène: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Épitope: AA 201-300

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC6 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Rat

Homologie: Human,Mouse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ERCC6

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ERCC6

Antigène: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Autre désignation: ERCC6 (ERCC6 Produits)

Synonymes: anticorps ARMD5, anticorps CKN2, anticorps COFS, anticorps COFS1, anticorps CSB, anticorps RAD26, anticorps UVSS1, anticorps 4732403I04, anticorps C130058G22Rik, anticorps ercc6, anticorps Ercc6, anticorps ERCC excision repair 6, chromatin remodeling factor, anticorps excision repair cross-complementing rodent repair deficiency, complementation group 6, anticorps excision repair cross-complementation group 6, anticorps DNA excision repair protein ERCC-6, anticorps ERCC6, anticorps Ercc6, anticorps ercc6, anticorps LOC100719487

Sujet:

Synonyms: CSB, CKN2, COFS, ARMD5, COFS1, RAD26, UVSS1, DNA excision repair protein ERCC-6, ATP-dependent helicase ERCC6, Cockayne syndrome protein CSB, ERCC6

Background: Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex (DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.

ID gène: 2074

UniProt: Q03468

Pathways: Réparation de l'ADN, Chromatin Binding