JNK anticorps (pThr183, pTyr185) (Cy5.5)

N° du produit ABIN2177528

L’anticorps anti-JNK Polyclonal Lapin est utilisé pour la détection de JNK dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IF (p) et IF (cc).

Aperçu rapide pour JNK anticorps (pThr183, pTyr185) (Cy5.5) (ABIN2177528)

Antigène: JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JNK est conjugé à/à la Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-JNK anticorps (Cy5.5)

Épitope: pThr183, pTyr185

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human MAPK9 around the phosphorylation site of Thr183+Tyr185

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur JNK

Antigène: JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

Autre désignation: MAPK8 +

Sujet:

Synonyms: MAPK8/MAPK9phospho T183/Y185, Mapk9, C Jun kinase 2, C Jun N terminal kinase 2, JNK 2, JNK-2, JNK 55, JNK2 alpha, JNK2 beta, JNK2alpha, JNK2B, JNK2beta, JNK55, Jun kinase, MAP kinase 9, MAPK 9, Mitogen activated protein kinase 9, P54 alpha, P54aSAPK, PRKM9, SAPK alpha, SAPK1a, SAPKa, Stress activated protein kinase JNK2.

Background: phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.

ID gène: 5601

Pathways: Signalisation MAPK, Signalisation WNT, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins