SHP1 anticorps (AA 501-595) (Biotin)

N° du produit ABIN2179191

Cet anticorps anti-SHP1 Polyclonal Lapin conjugué à Biotin (ABIN2179191) détecte spécifiquement SHP1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour SHP1 anticorps (AA 501-595) (Biotin) (ABIN2179191)

Antigène: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHP1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA

Détail du produit anti-SHP1 anticorps (Biotin)

Épitope: AA 501-595

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PTPN6/SHP1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur SHP1

Antigène: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Autre désignation: Shp1

Sujet:

Synonyms: HCP, HCPH, SHP1, SHP-1, HPTP1C, PTP-1C, SHP-1L, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6, Hematopoietic cell protein-tyrosine phosphatase, Protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, PTPN6, PTP1C

Background: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.

ID gène: 5777

UniProt: P29350

Pathways: Signalistation JAK/STAT, TCR Signaling, Signalisation TLR, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling