GRIN2B anticorps (AA 984-1104)

N° du produit ABIN220659

Détail du produit anti-GRIN2B anticorps

Antigène: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Épitope: AA 984-1104

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIN2B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Specificité: NMDAR2B. By Western blot it recognizes a 180kD band in rat brain membranes. Also recognizes a 70kD band (thought to be a contaminant). No reactivity to NMDAR2A or NMDAR2C by Western blot. Immunolabeling is blocked by preadsorption with the C-terminal fusion protein that was used to generate the antibody. Species Reactivity: Human, rat, mouse and fish.

Purification: Immunoaffinity purified

Immunogène: C-Terminal Fusion Protein of the NMDAR2B, aa 984-1104, 30kD.

Type of Immunogen: Fusion protein

Isotype: IgG

Information d'application

Indications d'application: Approved: IHC, IP, WB (1:200)

Usage: Western blotting 1:200 (NMDAR2B is present in high concentrations in the hippocampus). Immunoprecipitation: 3 μL will (under appropriate conditions) quantitatively immunoprecipitate all NMDAR2B in 200 μg of rat brain using solubilized hippocampal slices. Immunohistochemistry: Not suggested. Note: Above dilutions are with 35S-protein A, with ECL dilutions may need to be considerably higher to obtain specific immunolabeling.

Commentaires:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2. No preservative added.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur GRIN2B

Antigène: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Autre désignation: GRIN2B / NMDAR2B / NR2B (GRIN2B Produits)

Synonymes: anticorps NMDAR2B, anticorps GluN2B, anticorps MRD6, anticorps NR2B, anticorps hNR3, anticorps nmdar2b, anticorps nr2b, anticorps AW490526, anticorps Nmdar2b, anticorps glutamate ionotropic receptor NMDA type subunit 2B, anticorps glutamate receptor, ionotropic, N-methyl D-aspartate 2B L homeolog, anticorps glutamate receptor, ionotropic, NMDA2B (epsilon 2), anticorps GRIN2B, anticorps Grin2b, anticorps grin2b.L

Sujet: Name/Gene ID: GRIN2B
Subfamily: Glutamate receptor - ionotropic (NMDA receptor)
Family: Ion Channel

Synonyms: GRIN2B, GluN2B, GluR epsilon 2, NMDA receptor 2B, NMDAR2B, NR2B, NR3, MRD6, HNR3

ID gène: 2904

UniProt: Q13224

Pathways: Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity