IL7R anticorps
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- Antigène Voir toutes IL7R Anticorps
- IL7R (Interleukin 7 Receptor (IL7R))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL7R est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Réactivité croisée
- Souris, Rat (Rattus)
- Attributs du produit
- Concentration Definition: by UV absorbance at 280 nm
- Immunogène
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminus of mouse IL-7 receptor protein.
- Isotype
- IgG
- Top Product
- Discover our top product IL7R Anticorps primaire
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- Indications d'application
- This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 55 kDa in size corresponding to IL-7 receptor protein by western blotting in the appropriate cell lysate or extract.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.82 mg/mL
- Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- IL7R (Interleukin 7 Receptor (IL7R))
- Autre désignation
- IL-7 Receptor Alpha Chain (IL7R Produits)
- Synonymes
- anticorps IL7R, anticorps CD127, anticorps IL-7Ralpha, anticorps CDW127, anticorps IL-7R-alpha, anticorps IL7RA, anticorps ILRA, anticorps IL-7RA, anticorps interleukin 7 receptor, anticorps IL7R, anticorps Il7r
- Sujet
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This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Interleukin-7 is a glycoprotein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is an alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. The human and mouse sequence is nearly identical. In humans, severe combined immunodeficiency is caused by genetic defects in IL-7 receptor. The tyrosine residue at the 449 position is a critical signaling site of the intracellular domain of IL-7 receptor. This site is rapidly phosphorylated by janus kinases after the IL-7 receptor is engaged. IL-7 Receptor Alpha Chain Antibody is ideal for investigators interested in Immunology research.
Synonyms: IL7R alpha antibody, Interleukin 7 receptor alpha chain antibody, Interleukin 7 receptor antibody - ID gène
- 16197, 45269152
- UniProt
- P16872
- Pathways
- Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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