ALKBH1 anticorps

N° du produit ABIN2422379

Détail du produit anti-ALKBH1 anticorps

Antigène: ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALKBH1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity purification

Immunogène: Recombinant protein of human ALKBH1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ALKBH1

Antigène: ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))

Autre désignation: ALKBH1 (ALKBH1 Produits)

Synonymes: anticorps Alkbh, anticorps ABH, anticorps ABH1, anticorps ALKBH, anticorps alkB, anticorps hABH, anticorps 2700073G19Rik, anticorps Abh, anticorps alkB homolog 1, histone H2A dioxygenase, anticorps Alkbh1, anticorps ALKBH1

Sujet: This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites.

Poids moléculaire: Calculated MW: 44 kDa

Pathways: Réparation de l'ADN