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PHOX2A anticorps

PHOX2A Reactivité: Humain, Rat, Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2457912
  • Antigène Voir toutes PHOX2A Anticorps
    PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
    Reactivité
    • 32
    • 8
    • 7
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    Humain, Rat, Souris
    Hôte
    • 28
    • 3
    • 1
    Lapin
    Clonalité
    • 30
    • 2
    Polyclonal
    Conjugué
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PHOX2A est non-conjugé
    Application
    • 26
    • 13
    • 13
    • 11
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by peptide affinity chromatography method.
    Immunogène
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PHOX2A.
    Top Product
    Discover our top product PHOX2A Anticorps primaire
  • Indications d'application
    PHOX2A antibody can be used for detection of PHOX2A by ELISA at 1:1562500. PHOX2A antibody can be used for detection of PHOX2A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Conseil sur la manipulation
    As with any antibody avoid repeat freeze-thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PHOX2A antibody at -20 °C.
  • Antigène
    PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
    Autre désignation
    PHOX2A (PHOX2A Produits)
    Synonymes
    anticorps ARIX, anticorps CFEOM2, anticorps FEOM2, anticorps NCAM2, anticorps PMX2A, anticorps Arix, anticorps Phox2, anticorps Pmx2, anticorps Pmx2a, anticorps arix, anticorps sou, anticorps zgc:77364, anticorps phox2, anticorps xphox2a, anticorps paired like homeobox 2a, anticorps paired-like homeobox 2a, anticorps paired like homeobox 2a S homeolog, anticorps PHOX2A, anticorps Phox2a, anticorps phox2a, anticorps phox2a.S
    Sujet
    PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Poids moléculaire
    30 kDa
    ID gène
    401
    NCBI Accession
    NP_005160
    UniProt
    O14813
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