PHOX2A anticorps

N° du produit ABIN2457912

Détail du produit anti-PHOX2A anticorps

Antigène: PHOX2A (Paired-Like Homeobox 2a (PHOX2A))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHOX2A est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PHOX2A.

Information d'application

Indications d'application: PHOX2A antibody can be used for detection of PHOX2A by ELISA at 1:1562500. PHOX2A antibody can be used for detection of PHOX2A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PHOX2A antibody at -20 °C.

Détails sur PHOX2A

Antigène: PHOX2A (Paired-Like Homeobox 2a (PHOX2A))

Autre désignation: PHOX2A (PHOX2A Produits)

Synonymes: anticorps ARIX, anticorps CFEOM2, anticorps FEOM2, anticorps NCAM2, anticorps PMX2A, anticorps Arix, anticorps Phox2, anticorps Pmx2, anticorps Pmx2a, anticorps arix, anticorps sou, anticorps zgc:77364, anticorps phox2, anticorps xphox2a, anticorps paired like homeobox 2a, anticorps paired-like homeobox 2a, anticorps paired like homeobox 2a S homeolog, anticorps PHOX2A, anticorps Phox2a, anticorps phox2a, anticorps phox2a.S

Sujet: PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 30 kDa

ID gène: 401

NCBI Accession: NP_005160

UniProt: O14813