KDM6A anticorps

N° du produit ABIN2458408

Détail du produit anti-KDM6A anticorps

Antigène: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM6A est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UTX.

Information d'application

Indications d'application: UTX antibody can be used for detection of UTX by ELISA at 1:312500. UTX antibody can be used for detection of UTX by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store UTX antibody at -20 °C.

Détails sur KDM6A

Antigène: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Autre désignation: UTX (KDM6A Produits)

Synonymes: anticorps KABUK2, anticorps UTX, anticorps bA386N14.2, anticorps Utx, anticorps si:ch211-222m21.1, anticorps utx, anticorps kdm6a, anticorps tutx, anticorps uty, anticorps xtutx, anticorps lysine demethylase 6A, anticorps lysine-specific demethylase 6A, anticorps lysine (K)-specific demethylase 6A, anticorps lysine demethylase 6A S homeolog, anticorps KDM6A, anticorps LOC100539898, anticorps Kdm6a, anticorps kdm6a, anticorps kdm6a.S

Sujet: UTX is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.

Poids moléculaire: 154 kDa

ID gène: 7403

NCBI Accession: NP_066963

UniProt: O15550

Pathways: Tube Formation, L'effet Warburg