PDZK1 anticorps

N° du produit ABIN2458589

Détail du produit anti-PDZK1 anticorps

Antigène: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDZK1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PDZK1.

Information d'application

Indications d'application: PDZK1 antibody can be used for detection of PDZK1 by ELISA at 1:1562500. PDZK1 antibody can be used for detection of PDZK1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PDZK1 antibody at -20 °C.

Détails sur PDZK1

Antigène: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Autre désignation: PDZK1 (PDZK1 Produits)

Synonymes: anticorps xpdzk1, anticorps PDZK1, anticorps CAP70, anticorps CLAMP, anticorps NHERF-3, anticorps NHERF3, anticorps PDZD1, anticorps 1700023D20Rik, anticorps 2610507N21Rik, anticorps 4921513F16Rik, anticorps AI267131, anticorps AI314638, anticorps AL022680, anticorps D3Ertd537e, anticorps Pdzd1, anticorps mPDZK1, anticorps Clamp, anticorps PDZ domain containing 1, anticorps PDZ domain containing 1 L homeolog, anticorps PDZK1, anticorps pdzk1.L, anticorps pdzk1, anticorps Pdzk1

Sujet: PDZK1 is a scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. It may be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, it may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. PDZK1 may play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. PDZK1 may potentiate the CFTR chloride channel activity. It may function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. PDZK1 may be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.

Poids moléculaire: 41 kDa

ID gène: 5174

NCBI Accession: XP_001126710

UniProt: Q5T2W1