TNNT1 anticorps

N° du produit ABIN2458625

Détail du produit anti-TNNT1 anticorps

Antigène: TNNT1 (Slow Skeletal Troponin T (TNNT1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNT1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNNT1.

Information d'application

Indications d'application: TNNT1 antibody can be used for detection of TNNT1 by ELISA at 1:312500. TNNT1 antibody can be used for detection of TNNT1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TNNT1 antibody at -20 °C.

Détails sur TNNT1

Antigène: TNNT1 (Slow Skeletal Troponin T (TNNT1))

Autre désignation: TNNT1 (TNNT1 Produits)

Synonymes: anticorps ANM, anticorps NEM5, anticorps STNT, anticorps TNT, anticorps TNTS, anticorps TNNI1, anticorps AW146156, anticorps Tnt, anticorps sTnT, anticorps ssTnT, anticorps Fang2, anticorps tnTs, anticorps Tnnt, anticorps zgc:193831, anticorps zgc:193865, anticorps troponin T1, slow skeletal type, anticorps troponin I1, slow skeletal type, anticorps troponin T1, skeletal, slow, anticorps troponin T1, slow skeletal type S homeolog, anticorps troponin T type 1 (skeletal, slow), anticorps TNNT1, anticorps TNNI1, anticorps Tnnt1, anticorps tnnt1.S, anticorps tnnt1

Sujet: TNNT1 is a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year.This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 33 kDa

ID gène: 7138

NCBI Accession: NP_003274

UniProt: P13805