EIF2AK1 anticorps

N° du produit ABIN2458651

Détail du produit anti-EIF2AK1 anticorps

Antigène: EIF2AK1 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 1 (EIF2AK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF2AK1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EIF2AK1.

Information d'application

Indications d'application: EIF2AK1 antibody can be used for detection of EIF2AK1 by ELISA at 1:62500. EIF2AK1 antibody can be used for detection of EIF2AK1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store EIF2AK1 antibody at -20 °C.

Détails sur EIF2AK1

Antigène: EIF2AK1 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 1 (EIF2AK1))

Autre désignation: EIF2AK1 (EIF2AK1 Produits)

Synonymes: anticorps HCR, anticorps Hri, anticorps HRI, anticorps wu:fj97h09, anticorps zgc:153232, anticorps eukaryotic translation initiation factor 2 alpha kinase 1, anticorps eukaryotic translation initiation factor 2-alpha kinase 1, anticorps eukaryotic translation initiation factor 2 alpha kinase 1 L homeolog, anticorps EIF2AK1, anticorps eif2ak1, anticorps Eif2ak1, anticorps eif2ak1.L

Sujet: EIF2AK1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. The protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.The HRI gene is localized to 7p22 where its 3' end slightly overlaps the 3' end of the gene JTV1. The two genes are transcribed from opposite strands. Studies in rat and rabbit suggest that the HRI gene product phosphorylates the alpha subunit of eukaryotic initiation factor 2. Its kinase activity is induced by low levels of heme and inhibited by the presence of heme. Sequence Note: The sequence AF181071.1 is a chimeric mRNA clone. Only the heme-regulated initiation factor 2-alpha kinase region was propagated into this RefSeq record.

Poids moléculaire: 71 kDa

ID gène: 27102

NCBI Accession: NP_055228

UniProt: Q9BQI3

Pathways: Hepatitis C