Cadherin 4 anticorps

N° du produit ABIN2458919

Détail du produit anti-Cadherin 4 anticorps

Antigène: Cadherin 4 (CDH4)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 4 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDH4.

Information d'application

Indications d'application: CDH4 antibody can be used for detection of CDH4 by ELISA at 1:62500. CDH4 antibody can be used for detection of CDH4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CDH4 antibody at -20 °C.

Détails sur Cadherin 4

Antigène: Cadherin 4 (CDH4)

Autre désignation: CDH4 (CDH4 Produits)

Synonymes: anticorps cad4, anticorps rcad, anticorps R-cadherin, anticorps cadherin-4, anticorps AW120700, anticorps R-Cadh, anticorps Rcad, anticorps Cdh4l, anticorps zgc:136316, anticorps CAD4, anticorps RCAD, anticorps cadherin 4, anticorps cadherin 4, type 1, R-cadherin (retinal), anticorps Cadherin-4, anticorps cdh4, anticorps Cdh4, anticorps CDH4, anticorps cdh-4

Sujet: CDH4 gene is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 82 kDa

ID gène: 1002

NCBI Accession: NP_001785

UniProt: P55283

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size