KIRREL anticorps

N° du produit ABIN2459109

Détail du produit anti-KIRREL anticorps

Antigène: KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIRREL est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KIRREL.

Information d'application

Indications d'application: KIRREL antibody can be used for detection of KIRREL by ELISA at 1:312500. KIRREL antibody can be used for detection of KIRREL by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KIRREL antibody at -20 °C.

Détails sur KIRREL

Antigène: KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))

Autre désignation: KIRREL (NEPH1 Produits)

Synonymes: anticorps NEPH1, anticorps 6720469N11Rik, anticorps Kirrel1, anticorps Neph1, anticorps nephrin related, anticorps kirre like nephrin family adhesion molecule 1, anticorps kin of IRRE like (Drosophila), anticorps Smp_104390, anticorps Smp_140170, anticorps KIRREL1, anticorps Kirrel, anticorps Kirrel1

Sujet: KIRREL (NEPH1) is a member of the nephrin-like protein family, which includes NEPH2 and NEPH3. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2, MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).

Poids moléculaire: 66 kDa

ID gène: 55243

NCBI Accession: NP_060710

UniProt: Q5W0F9

Pathways: Regulation of Actin Filament Polymerization