PPP1R13B anticorps

N° du produit ABIN2459151

Détail du produit anti-PPP1R13B anticorps

Antigène: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP1R13B est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PPP1R13B.

Information d'application

Indications d'application: PPP1R13B antibody can be used for detection of PPP1R13B by ELISA at 1:312500. PPP1R13B antibody can be used for detection of PPP1R13B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PPP1R13B antibody at -20 °C.

Détails sur PPP1R13B

Antigène: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Autre désignation: PPP1R13B (PPP1R13B Produits)

Synonymes: anticorps ASPP1, anticorps p53BP2-like, anticorps p85, anticorps AI449786, anticorps AW545810, anticorps Tp53bp2, anticorps Trp53bp2, anticorps protein phosphatase 1 regulatory subunit 13B, anticorps protein phosphatase 1, regulatory subunit 13B, anticorps protein phosphatase 1 regulatory subunit 13B L homeolog, anticorps protein phosphatase 1, regulatory subunit 13Bb, anticorps protein phosphatase 1, regulatory (inhibitor) subunit 13B, anticorps PPP1R13B, anticorps Ppp1r13b, anticorps ppp1r13b.L, anticorps ppp1r13bb, anticorps ppp1r13b

Sujet: PPP1R13B is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.

Poids moléculaire: 119 kDa

ID gène: 23368

NCBI Accession: NP_056131

UniProt: Q96KQ4

Pathways: Signalisation p53