QPCT anticorps

N° du produit ABIN2459227

Détail du produit anti-QPCT anticorps

Antigène: QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp QPCT est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human QPCT.

Information d'application

Indications d'application: QPCT antibody can be used for detection of QPCT by ELISA at 1:62500. QPCT antibody can be used for detection of QPCT by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store QPCT antibody at -20 °C.

Détails sur QPCT

Antigène: QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))

Autre désignation: QPCT (QPCT Produits)

Synonymes: anticorps GCT, anticorps QC, anticorps sQC, anticorps QPCT, anticorps 5730422A13Rik, anticorps Qpctl1, anticorps RGD1562284, anticorps qpct, anticorps glutaminyl-peptide cyclotransferase, anticorps glutaminyl-peptide cyclotransferase (glutaminyl cyclase), anticorps glutaminyl-peptide cyclotransferase L homeolog, anticorps QPCT, anticorps Qpct, anticorps M6_Spy0443, anticorps M5005_Spy_0416, anticorps M28_Spy0404, anticorps CJA_2408, anticorps CCNA_02733, anticorps Tsp_03182, anticorps qpct.L

Sujet: QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. QPCT may be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86 % identical to that of bovine glutaminyl cyclase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 38 kDa

ID gène: 25797

NCBI Accession: NP_036545

UniProt: Q16769