FBXO8 anticorps

N° du produit ABIN2459823

Détail du produit anti-FBXO8 anticorps

Antigène: FBXO8 (F-Box Protein 8 (FBXO8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO8 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FBXO8.

Information d'application

Indications d'application: FBXO8 antibody can be used for detection of FBXO8 by ELISA at 1:62500. FBXO8 antibody can be used for detection of FBXO8 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FBXO8 antibody at -20 °C.

Détails sur FBXO8

Antigène: FBXO8 (F-Box Protein 8 (FBXO8))

Autre désignation: FBXO8 (FBXO8 Produits)

Synonymes: anticorps FBXO8, anticorps T24I21.22, anticorps T24I21_22, anticorps zgc:136842, anticorps FBS, anticorps FBX8, anticorps Fbx8, anticorps F-box protein 8, anticorps F-box and associated interaction domains-containing protein, anticorps F-box protein 8 L homeolog, anticorps FBXO8, anticorps fbxo8, anticorps AT2G16810, anticorps fbxo8.L, anticorps Fbxo8

Sujet: FBXO8 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO8 belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor (s) (ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor (s) (ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.

Poids moléculaire: 37 kDa

ID gène: 26269

NCBI Accession: NP_036312

UniProt: Q9NRD0