COL1A2 anticorps

N° du produit ABIN2460049

Détail du produit anti-COL1A2 anticorps

Antigène: COL1A2 (Collagen, Type I, alpha 2 (COL1A2))

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL1A2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COL1A2.

Information d'application

Indications d'application: COL1A2 antibody can be used for detection of COL1A2 by ELISA at 1:62500. COL1A2 antibody can be used for detection of COL1A2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store COL1A2 antibody at -20 °C.

Détails sur COL1A2

Antigène: COL1A2 (Collagen, Type I, alpha 2 (COL1A2))

Autre désignation: COL1A2 (COL1A2 Produits)

Synonymes: anticorps AA960264, anticorps AI325291, anticorps Col1a-2, anticorps Cola-2, anticorps Cola2, anticorps oim, anticorps OI4, anticorps Gas-6, anticorps alpha2(I), anticorps hm:zehn2357, anticorps wu:fa98d05, anticorps wu:fa99g10, anticorps wu:fb04c08, anticorps wu:fb11d06, anticorps zehn2357, anticorps coagulation factor II, thrombin, anticorps collagen, type I, alpha 2, anticorps collagen type I alpha 2 chain, anticorps collagen type I alpha 2 L homeolog, anticorps growth arrest specific 6, anticorps F2, anticorps Col1a2, anticorps col1a2.L, anticorps COL1A2, anticorps Gas6, anticorps col1a2

Sujet: COL1A2 is the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity.This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 150 kDa

ID gène: 1278

NCBI Accession: NP_000080

UniProt: P08123