FN3KRP anticorps

N° du produit ABIN2460081

Détail du produit anti-FN3KRP anticorps

Antigène: FN3KRP (Fructosamine 3 Kinase Related Protein (FN3KRP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FN3KRP est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FN3KRP.

Information d'application

Indications d'application: FN3KRP antibody can be used for detection of FN3KRP by ELISA at 1:1562500. FN3KRP antibody can be used for detection of FN3KRP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FN3KRP antibody at -20 °C.

Détails sur FN3KRP

Antigène: FN3KRP (Fructosamine 3 Kinase Related Protein (FN3KRP))

Autre désignation: FN3KRP (FN3KRP Produits)

Synonymes: anticorps FN3KL, anticorps FN3K-RP, anticorps fn3k, anticorps fn3kl, anticorps MGC145992, anticorps DKFZP469K211, anticorps RGD1304570, anticorps zgc:101634, anticorps fructosamine 3 kinase related protein, anticorps fructosamine-3-kinase-related protein, anticorps FN3KRP, anticorps Fn3krp, anticorps fn3krp

Sujet: FN3KRP phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein-bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation.FN3KRP and FN3K (MIM 608425) protect proteins from nonenzymatic glycation by phosphorylating the modified amino acid. This phosphorylation destabilizes the sugar-amine linkage and leads to spontaneous decomposition (Conner et al., 2004 [PubMed 15381090]).

Poids moléculaire: 34 kDa

ID gène: 79672

NCBI Accession: NP_078895

UniProt: Q9HA64