Cyclin T1 anticorps

N° du produit ABIN2460095

Détail du produit anti-Cyclin T1 anticorps

Antigène: Cyclin T1 (CCNT1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin T1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCNT1.

Information d'application

Indications d'application: CCNT1 antibody can be used for detection of CCNT1 by ELISA at 1:1562500. CCNT1 antibody can be used for detection of CCNT1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CCNT1 antibody at -20 °C.

Détails sur Cyclin T1

Antigène: Cyclin T1 (CCNT1)

Autre désignation: CCNT1 (CCNT1 Produits)

Synonymes: anticorps CG6292, anticorps Dmcyclin T, anticorps Dmel\\CG6292, anticorps ORE-14, anticorps P-TEFb, anticorps anon-74EFc, anticorps dT, anticorps p124, anticorps Cyclin-T1, anticorps ccnt, anticorps cyct1, anticorps CCNT, anticorps CYCT1, anticorps HIVE1, anticorps 2810478G24Rik, anticorps AI115585, anticorps CycT1, anticorps fi75b02, anticorps si:dkey-18f23.10, anticorps wu:fi75b02, anticorps Cyclin T, anticorps cyclin T1, anticorps cyclin T1 L homeolog, anticorps CycT, anticorps CCNT1, anticorps ccnt1, anticorps Ccnt1, anticorps ccnt1.L

Sujet: CCNT1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit.The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 81 kDa

ID gène: 904

NCBI Accession: NP_001231

UniProt: O60563