CHEK1 anticorps

N° du produit ABIN2460510

Détail du produit anti-CHEK1 anticorps

Antigène: CHEK1 (Checkpoint Kinase 1 (CHEK1))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHEK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHEK1.

Information d'application

Indications d'application: CHEK1 antibody can be used for detection of CHEK1 by ELISA at 1:312500. CHEK1 antibody can be used for detection of CHEK1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CHEK1 antibody at -20 °C.

Détails sur CHEK1

Antigène: CHEK1 (Checkpoint Kinase 1 (CHEK1))

Autre désignation: CHEK1 (CHEK1 Produits)

Synonymes: anticorps An08g10320, anticorps AO090003000441, anticorps CHK1, anticorps chk1, anticorps C85740, anticorps Chk1, anticorps rad27, anticorps id:ibd2720, anticorps zgc:56093, anticorps CHEK1, anticorps checkpoint kinase 1, anticorps serine/threonine-protein kinase chk1, anticorps serine/threonine-protein kinase Chk1, anticorps CAMK/CAMKL/CHK1 protein kinase Chk1, anticorps checkpoint kinase 1 S homeolog, anticorps CHEK1, anticorps ANI_1_2436074, anticorps AOR_1_768154, anticorps PTRG_04183, anticorps SJAG_01680, anticorps PAAG_04978, anticorps MCYG_03290, anticorps VDBG_03742, anticorps chek1.S, anticorps Chek1, anticorps chek1

Sujet: CHEK1 is required during normal S phase to avoid aberrantly increased initiation of DNA replication, thereby protecting against DNA breakage. Its expression is dispensable for somatic cell death and critical for sustaining G2 DNA damage checkpoint.

Poids moléculaire: 54 kDa

ID gène: 1111

NCBI Accession: NP_001265

UniProt: O14757

Pathways: Signalisation p53, Apoptose, Cycle Cellulaire, Réparation de l'ADN