KCNN2
Reactivité: Humain, Souris, Rat
WB, IHC, ICC, IF, IP
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
KCNN2 antibody can be used for detection of KCNN2 by ELISA at 1:62500. KCNN2 antibody can be used for detection of KCNN2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Conseil sur la manipulation
As with any antibody avoid repeat freeze-thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
For short periods of storage (days) store at 4 °C. For longer periods of storage, store KCNN2 antibody at -20 °C.
Antigène
KCNN2
(Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2))
anticorps KCNN2, anticorps SK2, anticorps KCa2.2, anticorps SKCA2, anticorps SKCa 2, anticorps hSK2, anticorps fri, anticorps potassium calcium-activated channel subfamily N member 2, anticorps potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2, anticorps KCNN2, anticorps Kcnn2
Sujet
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by KCNN2 is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. KCNN2 is a member of the KCNN family of potassium channel genes.