KCNQ2 anticorps

N° du produit ABIN2461151

Détail du produit anti-KCNQ2 anticorps

Antigène: KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))

Reactivité: Rat, Humain, Souris, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNQ2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNQ2.

Information d'application

Indications d'application: KCNQ2 antibody can be used for detection of KCNQ2 by ELISA at 1:12500. KCNQ2 antibody can be used for detection of KCNQ2 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KCNQ2 antibody at -20 °C.

Détails sur KCNQ2

Antigène: KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))

Autre désignation: KCNQ2 (KCNQ2 Produits)

Synonymes: anticorps BFNC, anticorps BFNS1, anticorps EBN, anticorps EBN1, anticorps EIEE7, anticorps ENB1, anticorps HNSPC, anticorps KCNA11, anticorps KV7.2, anticorps KVEBN1, anticorps KQT2, anticorps Nmf134, anticorps mKQT2.3, anticorps mKQT2.4, anticorps zgc:171872, anticorps potassium voltage-gated channel subfamily Q member 2, anticorps potassium voltage-gated channel, subfamily Q, member 2, anticorps potassium voltage-gated channel subfamily KQT member 2, anticorps potassium voltage-gated channel, KQT-like subfamily, member 2a, anticorps KCNQ2, anticorps Kcnq2, anticorps LOC100537363, anticorps kcnq2a

Sujet: The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by KCNQ2 and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).

Poids moléculaire: 93 kDa, 94 kDa, 96 kDa, 93 kDa, 44 kDa

ID gène: 3785

NCBI Accession: NP_004509

UniProt: Q5VYT9