MTA1 anticorps
-
- Antigène Voir toutes MTA1 Anticorps
- MTA1 (Metastasis Associated 1 (MTA1))
-
Reactivité
- Humain, Souris, Rat, Chien
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp MTA1 est non-conjugé
-
Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by protein A chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MTA1.
- Top Product
- Discover our top product MTA1 Anticorps primaire
-
-
- Indications d'application
- MTA1 antibody can be used for detection of MTA1 by ELISA at 1:62500. MTA1 antibody can be used for detection of MTA1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store MTA1 antibody at -20 °C.
-
- Antigène
- MTA1 (Metastasis Associated 1 (MTA1))
- Autre désignation
- MTA1 (MTA1 Produits)
- Synonymes
- anticorps Tex22, anticorps metastasis associated 1, anticorps metastasis associated 1 L homeolog, anticorps MTA1, anticorps Mta1, anticorps mta1.L
- Sujet
- MTA1 encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. MTA1 was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling.
- Poids moléculaire
- 47 kDa, 81 kDa
- ID gène
- 9112
- Pathways
- Chromatin Binding
-