NR2C1 anticorps

N° du produit ABIN2461692

Détail du produit anti-NR2C1 anticorps

Antigène: NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR2C1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR2C1.

Information d'application

Indications d'application: NR2C1 antibody can be used for detection of NR2C1 by ELISA at 1:62500. NR2C1 antibody can be used for detection of NR2C1 by western blot at 0.1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NR2C1 antibody at -20 °C.

Détails sur NR2C1

Antigène: NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))

Autre désignation: NR2C1 (NR2C1 Produits)

Synonymes: anticorps TR2, anticorps NR2C1, anticorps dor2, anticorps tr2-11, anticorps xDOR2, anticorps DKFZp468M0512, anticorps si:dkey-183c16.2, anticorps zgc:110672, anticorps 4831444H07Rik, anticorps 80.3, anticorps Eenr, anticorps Tr2-11, anticorps Tr2, anticorps Psg4, anticorps TR2-11, anticorps PSG9, anticorps nr2c1, anticorps nuclear receptor subfamily 2 group C member 1, anticorps nuclear receptor subfamily 2 group C member 1 S homeolog, anticorps nuclear receptor subfamily 2, group C, member 1, anticorps pregnancy specific beta-1-glycoprotein 4, anticorps nuclear receptor subfamily 2 group C member 1 L homeolog, anticorps NR2C1, anticorps nr2c1.S, anticorps nr2c1, anticorps Nr2c1, anticorps PSG4, anticorps nr2c1.L

Sujet: The nuclear orphan receptors NR2C1 represses transcription and binds DNA as a homodimer. NR2C1 binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. NR2C1 may function as a negative modulator to suppress androgen receptor function in prostate cancer. NR2C1 may exert an important repressor in regulating ER activity in mammary glands. The nuclear orphan receptors TR2 (NR2C1) and TR4 form a heterodimer that binds to the epsilon and gamma globin promoter DR1 sites

Poids moléculaire: 67 kDa

ID gène: 7181

NCBI Accession: NP_003288

UniProt: Q15625

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway