Aprataxin anticorps

N° du produit ABIN2462011

Détail du produit anti-Aprataxin anticorps

Antigène: Aprataxin (APTX)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aprataxin est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human APTX.

Information d'application

Indications d'application: APTX antibody can be used for detection of APTX by ELISA at 1:1562500. APTX antibody can be used for detection of APTX by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store APTX antibody at -20 °C.

Détails sur Aprataxin

Antigène: Aprataxin (APTX)

Autre désignation: APTX (APTX Produits)

Synonymes: anticorps aptx, anticorps APTX, anticorps LOC100284636, anticorps APRATAXIN-like, anticorps T10O8.20, anticorps T10O8_20, anticorps AOA, anticorps AOA1, anticorps AXA1, anticorps EAOH, anticorps EOAHA, anticorps FHA-HIT, anticorps 2410016G21Rik, anticorps AA388047, anticorps aprataxin, anticorps FHA-HIT, anticorps APRATAXIN-like protein, anticorps aprataxin L homeolog, anticorps aptx, anticorps APTX, anticorps CpipJ_CPIJ001673, anticorps LOC100284636, anticorps aptx.L, anticorps Aptx

Sujet: APTX is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. APTX may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.

Poids moléculaire: 38 kDa, 20 kDa, 20 kDa, 29 kDa

ID gène: 54840

NCBI Accession: NP_778243

UniProt: Q6JV85

Pathways: Réparation de l'ADN, Chromatin Binding