STAU1/Staufen anticorps

N° du produit ABIN2462172

Détail du produit anti-STAU1/Staufen anticorps

Antigène: STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAU1/Staufen est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STAU1.

Information d'application

Indications d'application: STAU1 antibody can be used for detection of STAU1 by ELISA at 1:62500. STAU1 antibody can be used for detection of STAU1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store STAU1 antibody at -20 °C.

Détails sur STAU1/Staufen

Antigène: STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))

Autre désignation: STAU1 (STAU1 Produits)

Synonymes: anticorps STAU1, anticorps DKFZp459A0124, anticorps CG5753, anticorps Dmel\\CG5753, anticorps Dmstau, anticorps STAU, anticorps Stau, anticorps Stauf, anticorps dStau, anticorps stau, anticorps XStau, anticorps XStau1, anticorps Staufen, anticorps Staufen1, anticorps MGC145034, anticorps 5830401L18Rik, anticorps AW549911, anticorps C85792, anticorps fi67e05, anticorps wu:fi67e05, anticorps zgc:77271, anticorps staufen double-stranded RNA binding protein 1, anticorps staufen, anticorps RNA binding protein homolog, anticorps staufen (RNA binding protein) homolog 1 (Drosophila), anticorps staufen double-stranded RNA binding protein 1 L homeolog, anticorps STAU1, anticorps stau, anticorps stau1, anticorps STAUFEN, anticorps Stau1, anticorps stau1.L

Sujet: STAU1 (Staufen) is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.

Poids moléculaire: 63 kDa, 56 kDa, 55 kDa, 55 kDa, 55 kDa

ID gène: 6780

NCBI Accession: NP_059347

UniProt: O95793

Pathways: Asymmetric Protein Localization