CES1 anticorps

N° du produit ABIN2462491

Détail du produit anti-CES1 anticorps

Antigène: CES1 (Carboxylesterase 1 (CES1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CES1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CES1.

Information d'application

Indications d'application: CES1 antibody can be used for detection of CES1 by ELISA at 1:312500. CES1 antibody can be used for detection of CES1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CES1 antibody at -20 °C.

Détails sur CES1

Antigène: CES1 (Carboxylesterase 1 (CES1))

Autre désignation: CES1 (CES1 Produits)

Synonymes: anticorps ACAT, anticorps CE-1, anticorps CEH, anticorps CES2, anticorps HMSE, anticorps HMSE1, anticorps PCE-1, anticorps REH, anticorps SES1, anticorps TGH, anticorps hCE-1, anticorps CESDD1, anticorps CES1, anticorps CES-K1, anticorps APLE, anticorps PMPMEase, anticorps CES, anticorps carboxylesterase 1, anticorps liver carboxylesterase 1, anticorps liver carboxylesterase, anticorps carboxylesterase 1 (monocyte/macrophage serine esterase 1), anticorps CES1, anticorps CpipJ_CPIJ013026, anticorps CpipJ_CPIJ016339, anticorps LOC100009551, anticorps LOC454097, anticorps LOC699486, anticorps LOC100050915

Sujet: CES1 is one of the enzymes responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia.Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene.

Poids moléculaire: 62 kDa, 63 kDa, 62 kDa, 8 kDa

ID gène: 1066

NCBI Accession: NP_001020365

UniProt: P23141

Pathways: Monocarboxylic Acid Catabolic Process