PPFIBP1 anticorps

N° du produit ABIN2462533

Détail du produit anti-PPFIBP1 anticorps

Antigène: PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPFIBP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PPFIBP1.

Information d'application

Indications d'application: PPFIBP1 antibody can be used for detection of PPFIBP1 by ELISA at 1:312500. PPFIBP1 antibody can be used for detection of PPFIBP1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PPFIBP1 antibody at -20 °C.

Détails sur PPFIBP1

Antigène: PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))

Autre désignation: PPFIBP1 (PPFIBP1 Produits)

Synonymes: anticorps liprin-beta-1, anticorps L2, anticorps SGT2, anticorps hSGT2, anticorps hSgt2p, anticorps 4632409B19Rik, anticorps AW214454, anticorps AW261454, anticorps PPFIA binding protein 1, anticorps PTPRF interacting protein, binding protein 1 (liprin beta 1), anticorps PTPRF interacting protein, binding protein 1 (liprin beta 1) S homeolog, anticorps Ppfibp1, anticorps ppfibp1, anticorps ppfibp1.S, anticorps PPFIBP1

Sujet: PPFIBP1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis.The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Poids moléculaire: 19 kDa, 113 kDa

ID gène: 8496

NCBI Accession: NP_803193